Article
Localization and phenotype-specific expression of ryanodine calcium release channels in C57BL6 and DBA/2J mouse strains.
Experimental eye research - 1 Nov 2011
Huang Wei, Xing Wei, Ryskamp Daniel A, Punzo Claudio, Križaj David
Abstract excerpt
The DBA/2J (D2) and C57BL6 (B6) mouse strains are widely used in research as models for anxiety, addiction and chronic glaucoma. D2, but not B6, animals develop elevated intraocular pressure (IOP) that leads to progressive degeneration of retinal ganglion cell (RGC) axons and perikarya. Here we compare the expression and localization of intracellular ryanodine receptor (RyR) Ca(2+) store mechanisms in retinas...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
