Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rod photoreceptor ribbon synapses in DBA/2J mice show progressive age-related structural changes.

PloS one - 1 Jan 2012

Fuchs Michaela, Scholz Michael, Sendelbeck Anna, Atorf Jenny, Schlegel Christine, Enz Ralf, Brandstätter Johann Helmut

Abstract excerpt

The DBA/2J mouse is a commonly used animal model in glaucoma research. The eyes of DBA/2J mice show severe age-related changes that finally lead to the degeneration of retinal ganglion cells and the optic nerve. Recent electroretinogram studies identified functional deficits, which suggest that also photoreceptor cells are involved in the pathological processes occurring in the DBA/2J mouse retina. In a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement C1q
Share to Electroretinography

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glaucoma

Share to Mice, Inbred DBA

Share to Optic Nerve

Share to Retinal Ganglion Cells

Share to Retinal Rod Photoreceptor Cells

Share to Synapses

Source

Open in PubMed Open full text

Identifiers

PMID: 22957094
DOI: 10.1371/journal.pone.0044645
PMCID: PMC3434146

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rod photoreceptor ribbon synapses in DBA/2J mice show progressive age-related structural changes.PMID 22957094Read ↗

Structural Changes of Retina in the Development of Glaucoma in DBA/2 MiceSemantic proximity Read ↗

Retinal neurodegeneration in the DBA/2J mouse?a model for ocular hypertensionSemantic proximity Read ↗

Genetic context modulates aging and degeneration in the murine retinaSemantic proximity Read ↗

Retinal degeneration in the mouse is rodless retina.Semantic proximity Read ↗

Early degeneration of photoreceptor synapse in Ccl2/Cx3cr1-deficient mice on Crb1(rd8) background.Semantic proximity Read ↗

Genetic context modulates aging and degeneration in the murine retinaSemantic proximity Read ↗

Preservation of Cone Photoreceptors after a Rapid yet Transient Degeneration and Remodeling in Cone-Only<i>Nrl</i><sup>−/−</sup>Mouse RetinaSemantic proximity Read ↗

A congenic C57BL/6J rd1 mouse model for retinal degeneration research.Semantic proximity Read ↗

Retinal organization in the retinal degeneration 10 (rd10) mutant mouse: a morphological and ERG study.Semantic proximity Read ↗

Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucomaSemantic proximity Read ↗

Complement Component 1Q (C1Q) Upregulation in Retina of Murine, Primate, and Human Glaucomatous EyesSemantic proximity Read ↗

BXD51: A Robust and Translational Mouse Model for Studying the Pathophysiology of GlaucomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.