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Article

LRP10 as a novel α-synuclein regulator in Lewy body diseases

2023-05-13

Abstract excerpt

Autosomal dominant variants in LRP10 have been identified in patients with Lewy body diseases (LBDs), including Parkinson’s disease (PD), Parkinson’s disease-dementia (PDD), and dementia with Lewy bodies (DLB). Nevertheless, there is little mechanistic insight into the role of LRP10 in disease pathogenesis. In the brains of non-demented individuals, LRP10 is typically expressed in non-neuronal cells like astrocyt...

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Identifiers and source

Literature Corpus work
04f7f546-2a2a-5c89-bf04-6781b30d9f3a
DOI
10.1101/2023.05.12.540510
Open publication

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LRP10 as a novel α-synuclein regulator in Lewy body diseasesDOI 10.1101/2023.05.12.540510
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