Article

Synergistic Roles of Bone Morphogenetic Protein 15 and Growth Differentiation Factor 9 in Ovarian Function

2001-06-01

Abstract excerpt

Knockout mouse technology has been used over the last decade to define the essential roles of ovarian-expressed genes and uncover genetic interactions. In particular, we have used this technology to study the function of multiple members of the transforming growth factor-β superfamily including inhibins, activins, and growth differentiation factor 9 (GDF-9 or Gdf9). Knockout mice lacking GDF-9 are infertile due to...

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Literature Corpus work: 04dc14d4-b387-5ed0-af66-3c0bc5fceac8
DOI: 10.1210/me.15.6.854

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