Article
Bmp15 mutations and ovarian function.
Molecular and cellular endocrinology - 31 May 2002
Galloway S M, Gregan S M, Wilson T, McNatty K P, Juengel J L, Ritvos O, Davis G H
Abstract excerpt
BMP15, also known as growth and differentiation factor 9B (GDF9B), is a member of the transforming growth factor beta superfamily (TGFbeta) which in humans, rodents and sheep is expressed exclusively in the oocyte. BMP15 is closely related to GDF9, another oocyte-specific member of this superfamily which has been shown to be essential for early ovarian folliculogenesis. Inactivation of the BMP15 gene in mice has...
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