Article

Comprehensive variant effect predictions of single nucleotide variants in model organisms

2018-05-02

Abstract excerpt

The effect of single nucleotide variants (SNVs) in coding and non-coding regions is of great interest in genetics. Although many computational methods aim to elucidate the effects of SNVs on cellular mechanisms, it is not straightforward to comprehensively cover different molecular effects. To address this we compiled and benchmarked sequence and structure-based variant effect predictors and we analyzed the impact...

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Literature Corpus work: 049a7e45-42dd-507e-9975-3472ec3c2f71
DOI: 10.1101/313031

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