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Article

VarMod: modelling the functional effects of non-synonymous variants.

Nucleic acids research - 1 Jul 2014

Pappalardo Morena, Wass Mark N

Abstract excerpt

Unravelling the genotype-phenotype relationship in humans remains a challenging task in genomics studies. Recent advances in sequencing technologies mean there are now thousands of sequenced human genomes, revealing millions of single nucleotide variants (SNVs). For non-synonymous SNVs present in proteins the difficulties of the problem lie in first identifying those nsSNVs that result in a functional change in...

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PMID: 24906884
DOI: 10.1093/nar/gku483
PMCID: PMC4086131

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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