Article
Possibility of correlating mutational profile of cancer with drugs suitable for treatment
2019-04-11
Abstract excerpt
Mutations constitute the genetic basis of cancer. Besides informing the molecular mechanisms where impingement of enzymes or receptor structure ultimately cascade to potentiation of cancer, genetic mutations could also help guide treatment strategies. Specifically, mutations at the DNA level could be correlated with structural changes at the protein level which holds implications for the relative binding affinity...
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Identifiers and source
- Literature Corpus work
- 049624bc-8bef-517a-9bdb-4c5260338fe0
- DOI
- 10.7287/peerj.preprints.27648v1