Article

Cucurbitacin B Controls M2 Macrophage Polarization to Suppresses Metastasis via Targeting JAK-2/STAT3 Signalling Pathway

2021-10-26

Abstract excerpt

<title>Abstract</title> <p>Background Colorectal cancer is one of the most high-risk human malignant tumors. Tumor-associated macrophages (TAMs) represent a substantial proportion of all tumor-infiltrating immune cells in the tumor microenvironment (TME), as it generally displays M1 or M2 phenotype with tumor-inhibiting or tumor-promoting activity. Cucurbitacin B has been reported to produce varieties of pharmac...

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Literature Corpus work: 048e4ad5-3d00-54a6-9942-088a44a495a0
DOI: 10.21203/rs.3.rs-1002730/v1

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