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Influence of CYP3A4 and CYP3A5 Genetic Variants on Clinical Outcomes in Methylprednisolone-Treated, Hospitalized COVID-19 Patients in Manaus, Brazil

2026-04-09

Abstract excerpt

<h4>Aims: </h4>: This study investigated whether common CYP3A4 and CYP3A5 variants are associated with clinical outcomes in hospitalized COVID-19 patients treated with MP in Manaus, Brazil. <h4>Methods: </h4>: A pharmacogenetic analysis was conducted on 100 hospitalized COVID-19 patients enrolled in a randomized, placebo-controlled clinical trial receiving heavy-dose intravenous MP (n = 49) or placebo (n = 51),...

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Literature Corpus work
0477f016-e0c5-5ce6-a913-c3e3f9680672
DOI
10.22541/au.177571298.89733492/v1
Open publication

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Influence of CYP3A4 and CYP3A5 Genetic Variants on Clinical Outcomes in Methylprednisolone-Treated, Hospitalized COVID-19 Patients in Manaus, BrazilDOI 10.22541/au.177571298.89733492/v1
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