Article

The aryl hydrocarbon receptor regulates epidermal differentiation through transient activation of TFAP2A

2023-06-08

Abstract excerpt

The aryl hydrocarbon receptor (AHR) is an evolutionary conserved environmental sensor identified as indispensable regulator of epithelial homeostasis and barrier organ function. Molecular signaling cascade and target genes upon AHR activation and their contribution to cell and tissue function are however not fully understood. Multi-omics analyses using human skin keratinocytes revealed that, upon ligand activation...

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Literature Corpus work: 043b9215-ed64-5a4c-ab34-46465592a7c1
DOI: 10.1101/2023.06.07.544032

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