Article
Aryl Hydrocarbon Receptor in Atopic Dermatitis and Psoriasis.
International journal of molecular sciences - 31 Oct 2019
Furue Masutaka, Hashimoto-Hachiya Akiko, Tsuji Gaku
Abstract excerpt
The aryl hydrocarbon receptor (AHR)/AHR-nuclear translocator (ARNT) system is a sensitive sensor for small molecular, xenobiotic chemicals of exogenous and endogenous origin, including dioxins, phytochemicals, microbial bioproducts, and tryptophan photoproducts. AHR/ARNT are abundantly expressed in the skin. Once activated, the AHR/ARNT axis strengthens skin barrier functions and accelerates epidermal terminal...
Topics
- Animals
- Dermatitis, Atopic
- Filaggrin Proteins
- Humans
- Oxidative Stress
- Polymorphism, Single Nucleotide
- Psoriasis
- Receptors, Aryl Hydrocarbon
- Skin
- T-Lymphocytes, Helper-Inducer
- T-Lymphocytes, Regulatory
