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Article

Heterogeneity of tumor-induced gene expression changes in the human metabolic network.

Nature biotechnology - 1 Jun 2013

Hu Jie, Locasale Jason W, Bielas Jason H, O'Sullivan Jacintha, Sheahan Kieran, Cantley Lewis C, Vander Heiden Matthew G, Vitkup Dennis

Abstract excerpt

Reprogramming of cellular metabolism is an emerging hallmark of neoplastic transformation. However, it is not known how the expression of metabolic genes in tumors differs from that in normal tissues, or whether different tumor types exhibit similar metabolic changes. Here we compare expression p...

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Identifiers

PMID: 23604282
DOI: 10.1038/nbt.2530
PMCID: PMC3681899

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23604282-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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