Article

T cell receptor repertoire signatures associated with COVID-19 severity

2021-12-02

Abstract excerpt

T cell receptor (TCR) repertoires are critical for antiviral immunity. Determining the TCR repertoires composition, diversity, and dynamics and how they change during viral infection can inform the molecular specificity of viral infection such as SARS-CoV-2. To determine signatures associated with COVID-19 disease severity, here we performed a large-scale analysis of over 4.7 billion sequences across 2,130 TCR rep...

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Literature Corpus work: 411e375e-f98b-5a8d-a2b2-6ec2579b4e7b
DOI: 10.1101/2021.11.30.470640

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