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Article

Intrinsic differences in hamster and mouse macrophage biology correlate with susceptibility to <i>L. donovani</i> infection

2025-08-02

Abstract excerpt

The basis for differential susceptibility to Leishmania ( L. ) donovani infection observed in individuals remains poorly understood. Here we address this important open question comparing bone marrow-derived macrophages from susceptible hamsters (hamBMDMs) and resistant mice (mBMDMs) to identify intrinsic cellular features that may contribute to host-specific outcomes. We first optimized and validated an experi...

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Identifiers and source

Literature Corpus work
03bb430d-38af-5438-af20-dc73a6d4c862
DOI
10.1101/2025.08.01.668127
Open publication

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Intrinsic differences in hamster and mouse macrophage biology correlate with susceptibility to <i>L. donovani</i> infectionDOI 10.1101/2025.08.01.668127
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