Article

Inhibition of the Extracellular Signal-regulated Kinase Pathway Restores the Discogenic Phenotype of Inflammatory Intervertebral Disc Cells

2021-06-08

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Intervertebral disc (IVD) degeneration is a spinal disease caused by trauma and/or repetitive mechanical overloading of the spine which triggers inflammatory response pathways. Long-term disc inflammation may lead to development of spinal pseudoarthrosis. The aim of the present study was to elucidate the role of the extracellular signal-regulated kinase (ERK) pa...

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Literature Corpus work: 03a851d6-9969-5f7b-b1ce-61674123acb9
DOI: 10.21203/rs.3.rs-579987/v1

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