Article

MicroRNA-338-3p as A Novel Therapeutic Target for Intervertebral Disc Degeneration

2020-11-10

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Recent studies have demonstrated the pivotal role played by microRNA (miRNA) in the etiopathogenesis of intervertebral disc degeneration (IDD). The aim of this current study is to investigate whether intra-discal delivery of miRNA can attenuate IDD development.<bold>Results:</bold> miR-338-3p expression was significantly increased in the nucleus pulposus (NP) of...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d6d0b456-8fcc-5182-b122-7ce850ba012f
DOI: 10.21203/rs.3.rs-101234/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-338-3p as A Novel Therapeutic Target for Intervertebral Disc DegenerationDOI 10.21203/rs.3.rs-101234/v1Read

MicroRNA-338-3p as a novel therapeutic target for intervertebral disc degeneration.Semantic proximity Read

Role of microRNAs in intervertebral disc degeneration (Review)Semantic proximity Read

The Mechanism and Function of <scp>miRNA</scp> in Intervertebral Disc DegenerationSemantic proximity Read

A Bioinformatic Analysis of MicroRNAs’ Role in Human Intervertebral Disc DegenerationSemantic proximity Read

The roles and perspectives of microRNAs as biomarkers for intervertebral disc degenerationSemantic proximity Read

Dysregulated miR-98 Contributes to Extracellular Matrix Degradation by Targeting IL-6/STAT3 Signaling Pathway in Human Intervertebral Disc DegenerationSemantic proximity Read

miR‐328‐5p Induces Human Intervertebral Disc Degeneration by Targeting WWP2Semantic proximity Read

The role of miRNA, lncRNA and circRNA in the development of intervertebral disk degeneration (Review)Semantic proximity Read

Characterization of microRNA expression profiles in patients with intervertebral disc degenerationSemantic proximity Read

The potential mechanisms and application prospects of non-coding RNAs in intervertebral disc degenerationSemantic proximity Read

Identification of microRNAs and target genes associated with the development of human intervertebral disc degeneration by bioinformatic analysis and verificationSemantic proximity Read

MicroRNA-140-3p alleviates intervertebral disc degeneration via KLF5/N-cadherin/MDM2/Slug axisSemantic proximity Read