Article

Retinoic acid inhibits the pyroptosis of degenerated nucleus pulposus cells by activating Sirt1-SOD2 signaling

2021-08-17

Abstract excerpt

<h4>Background: </h4> Intervertebral disc (IVD) degeneration is a common disease and initiated by the degeneration of nucleus pulposus (NP). The pyroptosis of degenerated NP cells (dNPCs) plays an important role in NP degeneration and may be a potential target in the treatment of IVD degeneration. The purpose of this study is to identify a feasible solution that can inhibit NP cell pyroptosis to therapy the degene...

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Literature Corpus work: 11b8297f-c3d9-5b73-9155-16ac234929c4
DOI: 10.21203/rs.3.rs-786450/v1

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