Article
MicroRNA-338-3p as a novel therapeutic target for intervertebral disc degeneration.
Experimental & molecular medicine - 1 Sept 2021
Jiang Hua, Moro Abu, Wang Jiaqi, Meng Dihua, Zhan Xinli, Wei Qingjun
Abstract excerpt
Recent studies have demonstrated the pivotal role played by microRNAs (miRNAs) in the etiopathogenesis of intervertebral disc degeneration (IDD). The study of miRNA intervention in IDD models may promote the advancement of miRNA-based therapeutic strategies. The aim of the current study was to investigate whether intradiscal delivery of miRNA can attenuate IDD development. Our results showed that miR-338-3p...
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