Article

Application of Genetic Polymorphisms in DNA Repair in the Prediction of Cancer Susceptibility and Clinical Outcome.

2003-09-01

Abstract excerpt

The capacity to repair damaged DNA is a basic tool by which the mammalian cell maintains its genetic integrity and prevents neoplasm; however, DNA repair function could be modified by genetic polymorphisms. Recent molecular epidemiological studies have indicated that these genetic variants occur in the normal population and can be used to predict individual cancer risk. Since variation in the function of these g...

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Literature Corpus work: 035fb6b4-803c-5ba5-9b37-5fdbc53d2c8d
DOI: 10.2174/1570160033476278

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