Article
Use of biomarkers to elucidate genetic susceptibility to cancer.
Environmental and molecular mutagenesis - 1 Jan 2000
Au William W, Salama Salama A
Abstract excerpt
Genetic variations have generally been accepted to be the major mechanism for the differences observed in susceptibility to cancer. However, extensive investigations on genotype-disease associations have not produced consistent results. The inconsistency may be caused by many factors, such as improper study design, insufficient sample size, complexity of the traits under investigation, heterogeneity of the study...
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