Article
Gene expression and polymorphisms of DNA repair enzymes: cancer susceptibility and response to chemotherapy.
Clinical lung cancer - 1 May 2007
Camps Carlos, Sirera Rafael, Iranzo Vega, Tarón Miquel, Rosell Rafael
Abstract excerpt
Platinum compounds play a central role in cancer chemotherapy. Although treatment is limited by side effects, they continue to have widespread application. One of the main aims of clinical or translational research in cancer is the search for genetic factors that could foresee treatment outcomes, in biologic activity and toxic effects. This genetic analysis might allow selection of patients who will have the...
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