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STAT1 and Its Crucial Role in the Control of Viral Infections

7 Apr 2022

Abstract excerpt

The signal transducer and activator of transcription (STAT) 1 protein plays a key role in the immune response against viruses and other pathogens by transducing, in the nucleus, the signal from type I, type II and type III IFNs. STAT1 activates the transcription of hundreds of genes, some of which have been well characterized for their antiviral properties. STAT1 gene deletion in mice and complete STAT1...

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PMID: 35456913
DOI: 10.3390/ijms23084095

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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