Article
Bovine CD14 gene characterization and relationship between polymorphisms and surface expression on monocytes and polymorphonuclear neutrophils.
BMC genetics - 8 Aug 2008
Ibeagha-Awemu Eveline M, Lee Jai-Wei, Ibeagha Aloysius E, Zhao Xin
Abstract excerpt
BACKGROUND: CD14 is an important player in host innate immunity in that it confers lipopolysaccharide sensitivity to cell types like neutrophils, monocytes and macrophages. The study was aimed at characterizing the CD14 gene of cattle for sequence variations and to determine the effect of variations on the expression of the protein on the surfaces of monocytes and neutrophils in healthy dairy cows. RESULTS: Five...
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