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Article

SNPs of CD14 change the mastitis morbidity of Chinese Holstein.

Molecular medicine reports - 1 Dec 2017

Li Jun, Wang Qiang, Chen Fanghui, Wang Haosen, Chen Jie, Wang Zhao, Huo Jiayan, Cai Yafei

Abstract excerpt

Gram‑negative (GN) bacterial infection is a main cause of bovine mastitis. The cluster of differentiation (CD) 14 gene serves an essential role in GN bacterium‑induced innate immune response. CD14 works as a bacterial lipopolysaccharide (LPS) receptor, combines with LPS‑liposaccharide binding protein complex, and causes cellular activation. However, the effects of CD14 single nucleotide polymorphisms (SNPs) on...

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Identifiers

PMID: 28990093
DOI: 10.3892/mmr.2017.7727

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