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<i>C9orf72</i> gene networks in the human brain correlate with cortical thickness in C9-FTD and implicate vulnerable cell types

2023-07-19

Abstract excerpt

<h4>Introduction</h4> A hexanucleotide repeat expansion (HRE) intronic to chromosome 9 open reading frame 72 ( C9orf72 ) is recognized as the most common genetic cause of amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and ALS-FTD. Identifying genes that show similar regional co-expression patterns to C9orf72 may help identify novel gene targets and biological mechanisms that mediate selecti...

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Literature Corpus work
02f1b31f-fa80-5a61-8902-d388fe22a96d
DOI
10.1101/2023.07.17.549377
Open publication

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<i>C9orf72</i> gene networks in the human brain correlate with cortical thickness in C9-FTD and implicate vulnerable cell typesDOI 10.1101/2023.07.17.549377
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