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Epigenetic analysis confirms no accelerated brain aging in schizophrenia

22 Aug 2017

Abstract excerpt

Epigenetic aging is associated with several biological mechanisms and diseases. We assessed two brain data sets, one small (n = 48) and one large (n = 392), to test epigenetic aging in schizophrenia. DNA methylation age from frontal cortex was significantly correlated with chronological age but no significant differences in DNA methylation age acceleration between schizophrenia cases and controls were observed in...

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PMID: 28871179
DOI: 10.1038/s41537-017-0026-4

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