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Article

Angiotensinogen Gene Silencing Reduces Markers of Lipid Accumulation and Inflammation in Cultured Adipocytes

1 Jan 2013

Abstract excerpt

Inflammatory adipokines secreted from adipose tissue are major contributors to obesity-associated inflammation and other metabolic dysfunctions. We and others have recently documented the contribution of adipose tissue renin-angiotensin system to the pathogenesis of obesity, inflammation, and insulin resistance. We hypothesized that adipocyte-derived angiotensinogen (Agt) plays a critical role in adipogenesis...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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Identifiers

PMID: 23483012
DOI: 10.3389/fendo.2013.00010

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