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Article

Multiplexed analysis of macrophage polarisation in pulmonary metastases of microsatellite stable colorectal cancer

2023-11-29

Abstract excerpt

Tumour-associated macrophages (TAMs) express a continuum of phenotypes ranging from an anti-tumoural M1-like phenotype to a pro-tumoural M2-like phenotype. During cancer progression, TAMs may shift to a more M2-like polarisation state, but the role of TAMs in CRC metastases is unclear. We conducted a comprehensive spatial and prognostic analysis of TAMs in CRC pulmonary metastases and corresponding primary tumours...

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Identifiers and source

Literature Corpus work
02ade8a6-e20b-5148-afaa-9e4f6edd3b13
DOI
10.21203/rs.3.rs-3663560/v1
Open publication

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