Article

Investigating Inherited Heart Diseases Using Human Induced Pluripotent Stem Cells

2024-09-27

Abstract excerpt

Inherited heart diseases (IHDs) are caused by genetic mutations that disrupt the physiological structure and function of the heart. Understanding the mechanisms behind these diseases is crucial for developing personalised interventions in cardiovascular medicine. Development of induced pluripotent stem cells, which can then be differentiated to any nucleated adult cell type, has enabled the creation of personalise...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2fd326b5-a42f-5f9e-9b69-e2b9ad45c651
DOI: 10.20944/preprints202409.2169.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Investigating Inherited Heart Diseases Using Human Induced Pluripotent Stem CellsDOI 10.20944/preprints202409.2169.v1Read

Modeling heart disease in a dish: from somatic cells to disease-relevant cardiomyocytes.Semantic proximity Read

Concise Review: Cardiac Disease Modeling Using Induced Pluripotent Stem CellsSemantic proximity Read

Human Pluripotent Stem Cell-Derived Cardiac Cells: Application in Disease Modeling, Cell Therapy, and Drug DiscoverySemantic proximity Read

Modelling inherited cardiac disease using human induced pluripotent stem cell-derived cardiomyocytes: progress, pitfalls, and potential.Semantic proximity Read

Human pluripotent stem cell-based models of heart development and diseaseSemantic proximity Read

Human Cardiac Organoids for Disease ModelingSemantic proximity Read

Heart in a dish – choosing the rightin vitromodelSemantic proximity Read

Human Induced Pluripotent Stem Cells as a Disease Model System for Heart FailureSemantic proximity Read

Inherited cardiac diseases, pluripotent stem cells, and genome editing combined—the past, present, and futureSemantic proximity Read

Generation of human chambered cardiac organoids from pluripotent stem cells for improved modelling of cardiovascular diseasesSemantic proximity Read

Transformative Potential of Induced Pluripotent Stem Cells in Congenital Heart Disease Research and TreatmentSemantic proximity Read

Generation of Heart Organoids Modeling Early Human Cardiac Development Under Defined ConditionsSemantic proximity Read