Article

NEGR1 can influence symptom severity in fluoxetine treated major depression disorder patients

2024-11-01

Abstract excerpt

<title>Abstract</title> <p> NEGR1 (neuronal growth regulator 1) is a cell adhesion molecule of the immunoglobulin (Ig) superfamily related to IgLON subgroup. NEGR1 promotes cell-cell adhesion and stimulates neurite growth of hypothalamic neurons and inhibits synapse formation. <italic>NEGR1</italic> is one of the genomic regions significantly associated with major depression disorder (MDD). The functional role...

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Literature Corpus work: 01f6518d-3538-5f6f-805a-fb78116480a0
DOI: 10.21203/rs.3.rs-4421084/v1

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