Article

Transgene-free hematopoietic stem and progenitor cells from human induced pluripotent stem cells

2017-08-21

Abstract excerpt

<h4>Introductory paragraph</h4> The successful production of Hematopoietic Stem and Progenitor Cells (HSPCs) from human pluripotent sources is conditioned by transgene delivery 1-5 . We describe here a dedicated and tractable one step, GMP-grade, transgene-free and stroma-free protocol to produce HSPCs from human induced pluripotent stem cells (hiPSCs). This procedure, applied to several sources of hiPSCs with e...

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Literature Corpus work: 01c95dba-eb0f-5bfb-81ce-d33eb489da3b
DOI: 10.1101/177691

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