Article
Early Development of Definitive Erythroblasts from Human Pluripotent Stem Cells Defined by Expression of Glycophorin A/CD235a, CD34, and CD36.
Stem cell reports - 8 Nov 2016
Mao Bin, Huang Shu, Lu Xulin, Sun Wencui, Zhou Ya, Pan Xu, Yu Jinfeng, Lai Mowen, Chen Bo, Zhou Qiongxiu, Mao Song, Bian Guohui, Zhou Jiaxi, Nakahata Tatsutoshi, Ma Feng
Abstract excerpt
The development of human erythroid cells has been mostly examined in models of adult hematopoiesis, while their early derivation during embryonic and fetal stages is largely unknown. We observed the development and maturation of erythroblasts derived from human pluripotent stem cells (hPSCs) by an efficient co-culture system. These hPSC-derived early erythroblasts initially showed definitive characteristics with...
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