Article

A Cytological F1 RNAi Screen for Defects in <i>Drosophila melanogaster</i> Female Meiosis

2024-01-15

Abstract excerpt

Genetic screens for recessive alleles induce mutations, make the mutated chromosomes homozygous, and then assay those homozygotes for the phenotype of interest. When screening for genes required for female meiosis, the phenotype of interest has typically been nondisjunction from chromosome segregation errors. As this requires that mutant females be viable and fertile, any mutants that are lethal or sterile when ho...

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Literature Corpus work: 01901aa7-be5c-5b67-8af5-1c8c054b5a24
DOI: 10.1101/2024.01.12.575435

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