Article

Irisin recovers osteoarthritic chondrocytes: a muscle-cartilage cross-talk boosted by physical activity

2020-04-07

Abstract excerpt

<title>Abstract</title> <p>Background Physical exercise favors weight loss and ameliorates both articular pain and function in patients suffering from osteoarthritis (OA). Irisin, a myokine released by skeletal muscles upon muscle contraction, has demonstrated to yield anabolic effects on different cell types. The study aimed to investigate the effect of irisin on human osteoarthritic chondrocytes (hOAC) in vitro...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 015f2ba3-7223-5f0c-8da6-20bd3eb5ff0b
DOI: 10.21203/rs.3.rs-20856/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Irisin recovers osteoarthritic chondrocytes: a muscle-cartilage cross-talk boosted by physical activityDOI 10.21203/rs.3.rs-20856/v1Read

Irisin enhances longevity by boosting SIRT1, AMPK, autophagy and telomeraseSemantic proximity Read

Irisin stimulates muscle growth-related genes and regulates adipocyte differentiation and metabolism in humansSemantic proximity Read

Browning of white fat: does irisin play a role in humans?Semantic proximity Read

Role and Functions of Irisin: A Perspective on Recent Developments and Neurodegenerative DiseasesSemantic proximity Read

Skeletal muscle as a gene regulatory endocrine organSemantic proximity Read

Tenascin-C-EGFR activation induces functional human satellite cell proliferation and promotes wound-healing of skeletal muscles via oleanic acidSemantic proximity Read

Irisin’s Dual Role in Malignant Tumors and Its Potential as a Biomarker and Therapeutic TargetSemantic proximity Read

Exercise-induced irisin improves follicular dysfunction by inhibiting IRE1α-TXNIP/ROS-NLRP3 pathway in PCOSSemantic proximity Read

Can Resistance Exercise Alter Irisin Levels and Expression Profiles of FNDC5 and UCP1 in Rats?Semantic proximity Read

Effects of physical activity on the link between PGC-1a and FNDC5 in muscle, circulating Ιrisin and UCP1 of white adipocytes in humans: A systematic reviewSemantic proximity Read

Irisin stimulates the release of CXCL1 from differentiating human subcutaneous and deep-neck derived adipocytes via upregulation of NFκB pathwaySemantic proximity Read

Irisin and FNDC5: effects of 12-week strength training, and relations to muscle phenotype and body mass composition in untrained women.Semantic proximity Read