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Article

Irisin’s Dual Role in Malignant Tumors and Its Potential as a Biomarker and Therapeutic Target

1 Aug 2025

Abstract excerpt

Irisin, a myokine secreted by skeletal muscle, has garnered significant attention for its multifaceted physiological roles and emerging potential as both a biomarker and therapeutic target in oncology. This review consolidates current understanding of irisin's impact across various malignancies, focusing on its complex regulation of tumorigenesis through interactions with key signaling pathways including...

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PMID: 40859977
DOI: 10.2147/dddt.s532658

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