Article

A Dual-Fluorescence Assay for Gene Delivery Vehicle Screening in Macrophages with an Inflammation-Inducible Reporter Construct

2024-08-07

Abstract excerpt

<h4>Background</h4> Macrophages are a promising target for therapeutics in various applications such as regenerative medicine and immunotherapy for cancer. Due to their plastic nature, macrophages can switch from a non-activated state to activated with the smallest environmental change. For macrophages to be effective in their respective applications, screening for phenotypic changes is necessary to elucidate the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0132b09f-b303-5b11-b04b-c81d4e378c38
DOI: 10.1101/2024.08.05.606664

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A Dual-Fluorescence Assay for Gene Delivery Vehicle Screening in Macrophages with an Inflammation-Inducible Reporter ConstructDOI 10.1101/2024.08.05.606664Read

Macrophage Gene Therapy: opening novel therapeutic avenues for immune disordersSemantic proximity Read

Engineered Self-Regulating Macrophages for Targeted Anti-inflammatory Drug DeliverySemantic proximity Read

Activatable Nanoreporters for Real-Time Tracking of Macrophage Phenotypic States Associated with Disease Progression.Semantic proximity Read

Macrophage-Based iNos Reporter Reveals Polarization and Reprogramming in the Context of Breast CancerSemantic proximity Read

Targeted delivery of RNA-based therapeutics enables functional analysis of macrophage subpopulationsSemantic proximity Read

Screening for new macrophage therapeutics.Semantic proximity Read

Macrophages in gene therapy: cellular delivery vehicles and in vivo targetsSemantic proximity Read

Optical profiling of macrophagesSemantic proximity Read

Lentiviral Delivery of RNAi for In Vivo Lineage-Specific Modulation of Gene Expression in Mouse Lung MacrophagesSemantic proximity Read

High throughput CRISPR screening identifies genes involved in macrophage viability and inflammatory pathwaysSemantic proximity Read

Hif-1α stabilisation polarises macrophages via cyclooxygenase/prostaglandin E2 <i>in vivo</i>Semantic proximity Read