Article

BMP7 increases UCP1-dependent and independent thermogenesis with a unique gene expression program in human neck area derived adipocytes

2021-09-27

Abstract excerpt

White adipocytes contribute to energy storage accumulating lipid droplets, whereas brown and beige adipocytes mainly function in dissipating energy as heat primarily via the action of uncoupling protein 1 (UCP1). Bone morphogenic protein 7 (BMP7) has been shown to drive brown adipocyte differentiation in mice. In this study, we have performed global RNA-sequencing and functional assays on adipocytes obtained from...

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Literature Corpus work: ea147e42-6d7f-5ec1-8a0c-befe1a7e8eb1
DOI: 10.1101/2021.09.27.461971

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