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Quantifying associations of genotype, proteinuria and eGFR with long-term kidney outcomes in Alport Syndrome using data from the UK National Registry of Rare Kidney Diseases (RaDaR)

2026-06-09

Abstract excerpt

<h4>Background</h4> Alport Syndrome (AS), caused by pathogenic variants in type IV collagen genes COL4A3/4/5 , is a leading monogenic cause of Kidney Failure (KF). Clinical course varies widely, and disease-specific predictors of progression relevant to clinical care and trial design remain incompletely defined. <h4>Methods</h4> In this retrospective cohort study of individuals with AS in the UK National Regis...

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Literature Corpus work: 0116d2d6-6267-5746-8b2c-2ff3f178d53a
DOI: 10.64898/2026.06.08.26355110

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