Article

Knockout of <i>Babesia bovis rad51</i> ortholog and its complementation by expression from the BbACc3 artificial chromosome platform

2019-04-11

Abstract excerpt

Babesia bovis establishes persistent infections of long duration in cattle, despite the development of effective anti-disease immunity. One mechanism used by the parasite to achieve persistence is rapid antigenic variation of the VESA1 cytoadhesion ligand through segmental gene conversion (SGC), a phenomenon thought to be a form of homologous recombination (HR). To begin investigation of the enzymatic basis for SG...

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Literature Corpus work: 0102d9c7-8f48-5706-a82c-dad6885f5ddd
DOI: 10.1101/606590

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