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Article

Cosmix-plexing: a novel recombinatorial approach for evolutionary selection from combinatorial libraries.

Journal of biotechnology - 1 Jun 2001

Collins J, Horn N, Wadenbäck J, Szardenings M

Abstract excerpt

The efficiency of existing combinatorial biological library methods has been moderate in terms of the success rates, the affinities of the ligands selected and the time and effort involved in trying to optimize the initial leads. Although mimicking natural evolution, existing strategies take little notice of the importance of recombination within a selected population to generate increased diversity. We present...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11526910
DOI: 10.1016/s1389-0352(01)00019-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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