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Article

Targeting LRH‑1 in hepatoblastoma cell lines causes decreased proliferation

15 Oct 2018

Abstract excerpt

Hepatoblastoma is the most common malignant liver tumor in children. Since it is often unresectable and exhibits drug resistance, the treatment of advanced hepatoblastoma is challenging. The orphan nuclear receptor liver receptor homolog‑1 (LRH‑1) serves prominent roles in malignancy; however, to the best of our knowledge, the role of LRH‑1 in hepatoblastoma remains unknown. In the present study, human...

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PMID: 30320362
DOI: 10.3892/or.2018.6793

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