Article

Ubiquitinome analysis of articular cartilage post mechanical injury reveals a differential ubiquitination pattern of a subset of DUBs and proteins linked to the ERAD cellular response

2022-01-20

Abstract excerpt

Understanding how connective tissue cells respond to mechanical stimulation is important to human health and disease processes in musculoskeletal diseases. Injury to articular cartilage is a key risk factor in predisposition to osteoarthritis. Here we identified a ubiquitin signature that is unique to injured articular cartilage tissue (the “injury ubiquitinome”). A total of 408 ubiquitinated peptides mapped to 11...

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Identifiers and source

Literature Corpus work: 0088961d-9884-5f99-a4dc-98ede3cad31b
DOI: 10.1101/2022.01.19.476879

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Ubiquitinome analysis of articular cartilage post mechanical injury reveals a differential ubiquitination pattern of a subset of DUBs and proteins linked to the ERAD cellular responseDOI 10.1101/2022.01.19.476879Read

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