Article

Tissue-specific and interferon-inducible expression of non-functional ACE2 through endogenous retrovirus co-option

2020-07-24

Abstract excerpt

<h4>Summary</h4> Angiotensin-converting enzyme 2 (ACE2) is an entry receptor for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), as well as a regulator of several physiological processes. ACE2 has recently been proposed to be interferon-inducible, suggesting that SARS-CoV-2 may exploit this phenomenon to enhance viral spread and questioning the efficacy of interferon treatment in Coronavirus diseas...

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Literature Corpus work: 00811cce-a8e7-5fe8-89f4-4c90dbcbbfd7
DOI: 10.1101/2020.07.24.219139

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