Article

Interferons and viruses induce a novel primate-specific isoform dACE2 and not the SARS-CoV-2 receptor ACE2

2020-07-20

Abstract excerpt

<h4>ABSTRACT</h4> Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which causes COVID-19, utilizes angiotensin-converting enzyme 2 (ACE2) for entry into target cells. ACE2 has been proposed as an interferon-stimulated gene (ISG). Thus, interferon-induced variability in ACE2 expression levels could be important for susceptibility to COVID-19 or its outcomes. Here, we report the discovery of a novel,...

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Literature Corpus work: ad93d05d-137f-533c-8b0d-5e86af0701c4
DOI: 10.1101/2020.07.19.210955

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