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Article

A high frequency of MDSCs in sepsis patients, with the granulocytic subtype dominating in gram-positive cases.

Journal of leukocyte biology - 1 Nov 2014

Janols Helena, Bergenfelz Caroline, Allaoui Roni, Larsson Anna-Maria, Rydén Lisa, Björnsson Sven, Janciauskiene Sabina, Wullt Marlene, Bredberg Anders, Leandersson Karin

Abstract excerpt

The causative microorganisms dictate the type of MDSC generated in sepsis patients, and a large proportion of PMN-MDSCs in gram-positive sepsis includes immunosuppressive myeloid blasts. MDSCs constitute a heterogeneous population of immature myeloid cells that potently suppress immune responses....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24929004
DOI: 10.1189/jlb.5HI0214-074R

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24929004-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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