Article

Alternative Splicing of Apoptosis Genes Promotes Human T Cell Survival

2022-06-17

Abstract excerpt

Alternative splicing occurs in the vast majority of human genes, giving rise to distinct mRNA and protein isoforms. We, and others, have previously identified hundreds of genes that change their isoform expression upon T cell activation via alternative splicing; however, how these changes link activation input with functional output remains largely unknown. Here we investigate how costimulation of T cells through...

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Literature Corpus work: 003a45d4-a2d5-5e20-85df-83aa747871f2
DOI: 10.1101/2022.06.17.496561

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