Article
Differential expression of human Fas mRNA species upon peripheral blood mononuclear cell activation.
The Biochemical journal - 15 Sept 1995
Liu C, Cheng J, Mountz J D
Abstract excerpt
Human Fas/Apo-1 is a cell-surface protein that mediates apoptosis upon ligation with Fas ligand. The gene lies on the long arm of chromosome 10, consists of nine exons, and spans more than 26 kb of DNA. We previously reported the presence of a Fas variant mRNA, designated as Fas delta TM, in huma...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Base Sequence
- Chromosome Mapping
- Chromosomes, Human, Pair 10
- DNA Primers
- Electrophoresis, Agar Gel
- Frameshift Mutation
- Gene Expression
- Gene Expression Regulation
- Genetic Variation
- Humans
- Lymphocyte Activation
- Lymphocytes
- Membrane Proteins
- Molecular Sequence Data
- Molecular Weight
- Polymerase Chain Reaction