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Single-cell transcriptomics predict novel potential regulators of acute epithelial restitution in the ischemia-injured intestine

2024-06-30

Abstract excerpt

<h4>ABSTRACT</h4> Intestinal ischemic injury damages the epithelial barrier predisposes patients to life-threatening sepsis unless that barrier is rapidly restored. There is an age-dependency of intestinal recovery in that neonates are the most susceptible to succumb to disease of the intestinal barrier versus older patients. We have developed a pig model that demonstrates age-dependent failure of intestinal barr...

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Literature Corpus work
002c02cb-0f73-5e7f-94a5-b6dc26ea202f
DOI
10.1101/2024.06.28.601271
Open publication

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Single-cell transcriptomics predict novel potential regulators of acute epithelial restitution in the ischemia-injured intestineDOI 10.1101/2024.06.28.601271
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