Article

Single-Cell Analysis Reveals Regional Reprogramming during Adaptation to Massive Small Bowel Resection in Mice

2019-04-24

Abstract excerpt

<h4>Background & Aims</h4> The small intestine (SI) displays regionality in nutrient and immunological function. Following SI tissue loss (as occurs in short gut syndrome, or SGS), remaining SI must compensate, or ‘adapt’; the capacity of SI epithelium to reprogram its regional identity has not been described. Here, we apply single-cell resolution analyses to characterize molecular changes underpinning adaptation...

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Literature Corpus work: 0cf990a9-07d8-56ea-a6ab-16ef683e6ef4
DOI: 10.1101/615054

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